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HLA-DQ2 Blockers

HLA-DQ2 is a class II heterodimer of HLA (human leukocyte antigen).  HLA-DQ2 is found in ~30-40% of the general population and represents a necessary but not sufficient requirement for developing celiac disease.  In celiac disease patients, the antigen presenting cells (APCs) bind to gluten peptide fragments via the HLA-DQ2 (or –DQ8 binding groove) which causes T-cell stimulation and a local and system immune response. 


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www.clinicaltrials.gov >>   

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Location

Alvine Pharmaceuticals, Inc.
Headquarters
75 Shoreway Rd., Suite B
San Carlos, CA 94070
view all contact info >>

Business Inquiries

Kirk Essenmacher, M.D., M.B.A.
T: (650) 596-2434
E: email BD >>

Clinical Inquiries

E: email info@alvinepharma.com >>

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